An unusual presentation of Erythema Multiforme in a paediatric patient

Erythema Multiforme

Erythema multiforme (EM) is an acute, vesiculobullous disease of skin and mucous membranes with symptoms ranging from mild to severe.

A complex interaction of different factors has been implicated to cause the condition; majority with a preceding herpes simplex infection.

This report describes an unusual presentation of erythema multiforme affecting the lips and oral mucosa of a healthy 7-year-old boy in the form of lip adherence.

Case report : Two weeks following eruption of oral ulcerations, a 7-year-old healthy boy patient developed severe erosive ulceration of both lips, causing complete lip adherence.

This was accompanied by marked bilateral submandibular and cervical lymphadenopathy, tremor and sweating.

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Clinical and laboratory investigations led to a diagnosis of erythema multiforme.

The patient was treated initially with gentle application of Vaseline between the lips using cotton buds in an attempt to release lip adhesion, followed by surgical release of the lips under general anaesthesia. Analgesics and topical steroid mouthwash were provided.


° Bani Hani, A, Nazzal, H, Webb, L et al. (2 more authors) (2015) An unusual presentation of erythema multiforme in a paediatric patient. European Archives of Paediatric Dentistry, 16 (3). pp. 297-302. ISSN 1818-6300 - https://doi.org/10.1007/s40368-015-0181-0

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