An update on primary teeth pulpotomy medicaments


Vital pulpotomy is the clinical treatment of choice for primary teeth with exposed pulp.

Pulpotomy can be defined as the surgical removal or amputation of the coronal pulp of the vital tooth.

This step is generally followed by the placement of a particular medicament over the intact stump to fix, mummify or stimulate repair of the remaining radicular pulp.

There have been three common medicaments used fot pulpotomy in primary teeth: formocresol, calcium hydroxide and glutaraldehyde; however, other medicaments have been investigated for pulpotomy procedures, including electrosurgery and laser, ferric sulfate freeze-dried bone, bone morphogenetic protein, osteogenic protein-1, the novel anti-inflammatory agent tetrandrine, collagen, feracrylum, glass ionomer, mineral trioxide aggregate (MTA), lyophilized freezefdried platelet-derived enamel matrix derivate, sodium hypochlorite, Portland cement, nanohydroxyapatite, calcium-enriched mixture, calcium phosphate cement, and Allium sativum oil.

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The clinical successes of these medicaments have a differed from each other in biological compatibility, healing capabilities, mutagenicity, cytotoxicity, histological responde and carcinogenic potential.

Therefore, the aim of this study was to review the history and the scientific literature published on pulpotomy medicaments and to present the findings of these studies.


Yousef H Al-Dlaigan

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