ORAL PATHOLOGY : Developmental anomalies affecting the morphology of teeth

The tooth is a specialized part of the human body, understanding the development of which is enigmatic and still challenging.

The successful development of tooth depends on a complex reciprocal interaction between the dental epithelium and underlying ectomesenchyme. The interaction involves a complex series of molecular signals, receptors and transcription control systems.

Anomaly is a deviation from what is regarded as normal.

Disturbance of the epithelium and mesenchymal interactions can markedly alter the normal odontogenesis leading to the developmental anomaly of teeth.

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Depending on the developmental stage in which the alteration has taken place, different anomalies could take place e.g. anomalies of number, structure, size and/or shape.

Developmental dental anomalies are marked deviations from the normal color, contour, size, number, and degree of development of teeth.

Local as well as systemic factors may be responsible for these developmental disturbances. Such influences may begin before or after birth, hence both the dentition might be affected.


Ashish Shrestha / Vinay Marla / Sushmita Shrestha / Iccha K Maharjan

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